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Ginger and cancer

"Dear Jeff,

"In the light of your article in this morning's Herald we are sending you the enclosed information about our experience with thyroid cancer in our dog, Annabelle, and

treatment with a ginger extract. On the surface, it seems that the ginger extract has caused Annabelle's thyroid cancer to regress.

"Of course, there might be another reason for the cancer to regress. For instance, when the vet took the biopsy the cancer was opened up. This might have given

normal white blood cells an opportunity to invade the cancer.

"Nevertheless, the reason that we gave the ginger extract to Annabelle is that we had heard a few anecdotes about the specific ginger extract causing a few people to lose signs of their cancer. This is why we feel that the ginger extract helped Annabelle.

"One of the people we were able to check on is the mother of Paul Bevan at the ABC, Newcastle, who has used the ginger extract. [Paul Bevan told early this year of the improvement in his mother's after she started using the ginger extract, Digest Easy, when she was diagnosed with an inoperable cancer.]

"In order that we could have objective evidence of Annabelle's experience we obtained the relevant vet and pathology records, copies of which are enclosed.

We prepared the enclosed material and forwarded it to Biohawk (Professor Cliff Hawkins) and to the Korean research group. This group has found that the active

ingredient in ginger, and in Digest Easy, 6-gingerol, inhibits the action of VEGF (vascular endothelial growth factor) and FGF (fibroblast growth factor). Both of these

growth factors are commonly in elevated concentrations in cancers. Additionally, Annabelle's cancer had a lot of blood vessels, necessitating suturing. Consequently,

Annabelle's form of cancer might have been peculiarly suited to the action of gingerol.

"Anyway, we thought that, in view of your interest and since your readers are interested in your views on cancer and treatments, you might be interested in this

documented case of thyroid cancer in Annabelle."

Signed Barry and Moira Boettcher, of New Lambton.

The following is a synopsis prepared by Barry Boettcher and attached to the above letter.

"In late 2009 Annabelle developed a lump on the right side of the neck. It grew from a small lump to a considerable size over the course of some weeks. The

increase in size was readily detectable on a week-by-week basis.

"In late December 2009 a biopsy was taken of the lump and Annabelle was diagnosed with a thyroid carcinoma. Her thyroid function was low.

"Annabelle's treatment consisted solely of her previous diet plus 15ml Digest Easy and a teaspoon of tinned fish three times daily (morning, midday and night).

"Instead of Annabelle's lesion growing after the biopsy had been taken, as was anticipated, the lesion decreased in size on a day-by-day basis. It was possible for me to detect the constant decrease in size. Within a month, I could not palpate the lesion.

"In May 2010 Annabelle was examined by the vet who examined her in December 2009. He could find no evidence of the original thyroid lesion. A thyroid function test gave a value similar to the previous test.

"There are credible reports in the medical literature of gingerol, the main active component of ginger and a major constituent of Digest Easy, being active against

growth of cancers, inhibiting the growth factor-induced proliferation of endothelial cells (cells lining blood and other vessels), inhibiting angiogenesis (the growth of

blood vessels) and inducing growth arrest and apoptosis (programmed cell death) in human colorectal cancer cells.

"It seems that, in view of Annabelle's documented experience and reports in the medical literature, further research is warranted on the possible benefits of gingerol, or ginger extracts, in disease and, in particular, cancer."

Barry Boettcher is an emeritus professor of biology at Newcastle University and a highly respected forensics expert, and his credibility in these fields is such that I've chosen to run the letter and synopsis in full.

Digest Easy is a product of Biohawk (biohawk.com.au), a Queensland firm, and has been developed by a retired professor of chemistry, Cliff Hawkins, as a digestive aid to neutralise the effect of certain proteins in people with food intolerances and allergies.

Dr Hawkins hopes that the ginger extracts he has developed will be the subject this year of clinical trials in the treatment of certain cancers.

Any cancer patient intending to take Digest Easy should, of course, discuss that with their doctor.

You may recall in my blog "Cancer-fighting stuff" of last week that I wrote that the only knowledge I had of cancer-fighting stuff was that it was all crap, and that applied also to prayers to a certain saint in waiting. Barry and Moira Boettcher have taken me to task gently and reminded me of the value of an open mind. Should I expect a letter from the Pope?

Dr Hawkins has accepted my invitation to discuss his ginger-extract products and to answer your queries today.

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comments


Date: Newest first | Oldest first
Did this idea come from China? Have the Chinese been using ginger for thousands of years, or is that Ginseng? I have a pot of ginger on the verandah that grows lovely ornamental foliage. I would imagine that the ginger root you buy from a supermarket would multiply nicely if it was planted.
Posted by Tel, 31/05/2010 5:16:30 AM, on The Herald
“Researchers polled 1,144 doctors for the study, which was published in the Archives of Internal Medicine, The Los Angeles Times reported. Only 1 percent said they believe religious faith and spirituality have a negative effect, while 2 percent said it has no effect and 12 percent said they think the positive and negative effects are balanced. Asked about their own religious beliefs, 54 percent said they think God sometimes intervenes to help patients, 28 percent do not and 18 percent are agnostic. Dr. John Robertson, chief heart surgeon at St. John's Health Center in Santa Monica, Calif., told the newspaper he has observed that patients with a strong religious faith are more optimistic and recover more quickly. Other doctors say churches and other religious organizations can provide emotional and practical support to patients. Some doctors said the downside of religious belief is that patients can believe their illnesses are divine punishment. Some religions also stigmatize people with AIDS.” Copyright 2007 by United Press International http://www.physorg.com/news964309 07.html
Posted by Anne Egan-Plaizier, 31/05/2010 7:24:17 AM, on The Herald
This is great news,it is painful to lose a good dog, so I am happy to hear this dog has been cured. I wish I'd have been given an option like this when our 8 year old dog had been diagnosed with liver cancer. At least we may have had her for a few more years, she may have still been here today.
Posted by Mark S(Phoney Clown), 31/05/2010 9:51:38 AM, on The Herald
Another interesting topic Jeff. I know nothing of cancer fighting properties of ginger, however, I have taken ginger for nausea (since childhood) and it works for me. Dr Hawkins, might shed some light on this aspect of Ginger. Slightly off topic, I was reading an article on 'bitter melon' and its effect on breast cancer cell growth which is very interesting. My question for Dr Hawkins is: How critical is the dosage of the substance to the effect or outcome ? Put simply, if you don't take enough of the substance then it will have no effect and people will say that it doesn't work and that it's just quackery; when, had they increased the dose it would have shown some effect.
Posted by Pie N Peas, 31/05/2010 10:07:32 AM, on The Herald
The DigestEasy is sold as an aid to digestion of proteins that our digestive system cannot digest. It is made from ginger, turmeric and galangal. These gingers have over 200 bioactive compounds including some special enzymes that specifically target proteins that are rich in peptide groups that make the proteins non-digestible. The Biohawk gingers in contrast to other ginger products have these enzymes present at a standardized, high activity. People choose to take our products for food intolerance and allergies and for other diseases . The impact is related to dose taken and body weight. We studied many food crops before we chose the gingers. The gingerols and curcumin etc will be assisting but cancer cells have on their membranes proteins that have similar peptide groups to the foods we cannot digest. The ginger enzymes should be able to give the cancer cells a hair cut and remove their activity because of the specific structures of the proteins on the cancer cell membranes. Formal clinical trials have not as yet been conducted. I am happy to answer further questions.
Posted by cliff, 31/05/2010 11:26:40 AM, on The Herald
This is Cliff Hawkins, whose firm, Biohawk, has the product Digest Easy. As you can read he is willing to answer questions.
Posted by Jeff Corbett on 31/05/2010 11:40:55 AM
I have read that ginger removes toxins from the body. Is this the cancer fighting component of ginger Dr Hawkins? If not, I would like to know just what ginger does in its fight against cancer.
Posted by Anne Egan-Plaizier, 31/05/2010 11:27:41 AM, on The Herald
Dont you just love those wispy flaky statements like"removes toxins from the body"?What toxins? How? New agers love these woolly assertions - meanwhile the herbo naturoflakeologist charges you $80 cold hard cash for some vile tasting goo that comes from godknows where. Anyway--ginger-well its like chicken soup--cant hurt,might help.Go for it.
Posted by snooze, 31/05/2010 12:16:39 PM, on The Herald
I have spent time with a number of paediatric oncologists and they do not suggest ginger. What is your expectation of mainstream medicine in regard to alternatives?
Posted by chaff and oats, 31/05/2010 12:33:29 PM, on The Herald
Q. Are the gingerols and curcumin etc effected by stomach acid ? And are there any scientific papers (worldwide) published on gingerols effect on proteins, OR is all the evidence purely anectodal ?
Posted by Pie N Peas, 31/05/2010 12:46:14 PM, on The Herald
I have a few questions for Cliff. How well do the enzymes survive the acidic pH of the stomach. Enzymes are notoriously labile, so how much remains bioavailable after passage through the gut. Are you able to standardise your extracts? One of the great problems of any herbal extract is the varietal and seasonal variation of the “active” compounds. Often standardisation is based on one plant component, which may or may not have any activity. I assume the action of 6-gingerol, inhibiting the action of VEGF (vascular endothelial growth factor) and FGF (fibroblast growth factor) has only been tested in-vitro, which may not have any relevance at all to oral administration of a ginger extract. And inhibition of angiogenesis via VEGF inhibition may indeed be a very bad thing for those with slow occlusion of coronary arteries and blood vessels, as it may prevent formation of new blood vessels (collateralisation). Still it is interesting stuff, but certainly a properly designed series of studies is required. Possible tumour regression in one dog is interesting, but nothing to get excited about yet.
Posted by Directeur Sportif, 31/05/2010 12:58:21 PM, on The Herald
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Jeff Corbett
Bend the online ear of the Hunter's most provocative columnist.

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