The St Pius X Adamstown community knew the show had to go on when a fire threatened its new theatre at the end of June.
The fire, set by vandals, razed the Sister Marie Hall, formerly known as St Anne's Library, but the school's newly-built theatre was saved.
The 570-seat auditorium, christened The Factory, is thought to be the largest in the Hunter and will go through a baptism of fire when students hit the stage this week in Aspire.
VIDEO: See a sneak peak of the performance and learn more about Aspire.
Video by Darren Pateman
Aspire is the first annual Maitland-Newcastle Diocese Catholic Schools performing arts night.
It features the top talent of 80 students from the region's 55 Catholic primary and high schools.
Each of the students had to pass auditions for regional voice, drama, instrumental or dance ensembles.
The ensembles were formed for an extension program for talented students.
Music ranging from Adele to Abba added to the theme of this year's production, This Is Me.
Aspire executive officer Lisa Little said organisers were expecting full houses for all four performances between today and Saturday.
"This, we hope, will rival anything else that's out there in terms of quality and any other systems," she said.
"We knew the talent was out there in our schools. This was a chance to reveal that."
For tickets, call 4929 1977.